Mature nerve cells

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These induced stem cells are similar to those that occur during the early embryonic development of the central nervous system. They can be modified and multiplied indefinitely in the culture dish and can represent an important basis for the development of regenerative therapies. Stem cells are considered to be the all-rounders of our tissues: In , the Japanese scientist Shinya Yamanaka recognized that such cells could also be produced in the laboratory - from mature body cells.
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The University of Texas UT Southwestern researchers had originally set out to prompt supporting glial cells to develop into dopamine-producing neurons, but their approach instead triggered a type of GABA-producing striatal nerve cells known as medium spiny neurons, to convert directly into dopaminergic DA neuron-like cells iDALs. These neurons displayed markers and electrophysiological properties that mirror those of native mature dopamine-producing nerve cells that are normally found in other areas of the brain. The UT Southwestern scientists' latest work, focused on reprogramming glial cells, was founded on their previous studies indicating that ectopic SOX2 can reprogram resident striatal glial cells in the adult mouse brain into neuronal progenitors, which then differentiate into mature neurons when the animals are treated with the small molecule valproic acid. Using this type of approach the team hoped to induce glial cells in the adult mouse brain to differentiate into dopaminergic neurons. The genes were delivered by viral vector directly into the striatum, a region of the brain that is rich in GABA-producing medium spiny neurons, a nerve cell type that controls motor function. Dopamine-producing neurons are generally located elsewhere in the brain, but do put out connections that control the striatal medium spiny neurons.
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January 22, , Max Planck Society Stem cells turn into nerve cells: Biomaterials, Many clinicians have pinned their hopes on stem cells. Stem cells could, for example, replace nerve cells after a stroke. However, until now it has not been possible to observe the process of live stem cells developing into fully functional nerve cells. Now, researchers at the Max Planck Institute for Metabolism Research in Cologne have developed a novel method for studying such processes in the living brain, enabling them to observe how human stem cells transplanted into the cerebral cortex of mice develop into mature functional nerve cells.
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All muscle cells and nerve cells use an action potential and also obey the all-or-none law Share to: How do nerve cells muscle cells and blood cells compare? Blood cells depends on what type of blood you are talking about white blood cells help protect your body fr…om sickness and red blood cells carry oxygen to your lungs allowing you to breath both are essential for living Electric stimulants which trigger the cells themselves Share to: How big is a human nerve cell? The soma body of a neuron can be from about 5 to micrometers in diameter wikipedia.
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